One of the biggest problems facing large-handed gamers is simply finding a mouse that feels comfortable to use. After all, nothing throws you off your game like having to scrunch your hand up to use a small gaming mouse. Sound like a problem you’ve faced before? If that’s the case, it’s time to start looking into the best gaming mice for large hands.

No, you’re not going to find a bigger gaming mouse equivalent of a Logitech G Pro X Superlight or any of the popular ultralight mice right now. That’s just not going to happen. But there are still a handful of great larger gaming mice that are worth checking out, so let’s get right to it.

The Best Gaming Mice for Big Hands

A couple of quick notes before we start. Firstly, the mouse widths listed here are grip widths, not the maximum widths. Grip width shows how wide a mouse is where you rest your thumb and ring fingers, and we feel that that most accurately represents the experience of holding a mouse.

Secondly, while these mice are big, they still may not be big enough if you have huge hands. Ideally, you want to find one that measures about 60% of your hand’s width and length, but this might be difficult if your hands are enormous. Never measured your hand before? Check out the buying guide in our list of the best small mice for an easy way to do so.

1. Razer DeathAdder V2 Pro

When it comes to large gaming mice, the Razer DeathAdder shape is one of the classics of the style. Its curvy, right-handed design fits nicely in a palm grip, allowing the fingers to rest in a more relaxed manner than ambidextrous mice. In that sense, it’s not too dissimilar from other mice on our list.

But there are a couple of reasons the V2 Pro is our overall favorite. First is its slightly narrower grip width, which makes it a safer recommendation for a variety of grip styles. Secondly, the V2 Pro has modern features that you don’t always get on large gaming mice. These include 100% PTFE feet, optical switches, wireless operation, and relatively lightweight construction.

That final point is arguably the most appealing part. The older DeathAdder mice tended to weigh around 100 grams (3.5 oz), but the V2 Pro comes in at a relatively svelte 88 grams (3.1 oz). It’s still significantly heavier than the best lightweight gaming mice, but it’s probably as close as you’re going to get in a gaming mouse for big hands.

As far as the wireless connectivity goes, the V2 Pro supports Razer’s low-latency HyperSpeed dongle as well as standard Bluetooth. Razer claims 70 hours of battery life with the low-latency dongle and a reasonably impressive 120 hours via Bluetooth. The charging cable is braided and lightweight, which is a welcome touch.

The DeathAdder V2 Pro sports five onboard memory slots, which retain settings such as button programming and DPI. However, you’ll still need Synapse running to tweak certain parameters. The lighting and lift-off distance, for example, aren’t saved to the onboard memory. We can see this being a deal-breaker for some, but we feel it’s an acceptable situation overall.

Overall, the DeathAdder V2 Pro is a solid update to a much-loved gaming mouse. The shape has always been great, but the V2 Pro’s weight reduction and wireless connectivity make it the best DeathAdder yet. On balance, it’s the best gaming mouse for big hands in our book.

Not into wireless mice? The DeathAdder V2 has the same improvements as the V2 Pro at a lower price.

2. Zowie EC1

Zowie’s EC1 shape is one of the most loved and copied in the gaming mouse world, and for a good reason. Like the Razer DeathAdder, the EC1 is a large ergonomic mouse, perfect for palm grippers and large-handed alike.

It has a wider grip width and is slightly less curved than the DeathAdder, but both are overall more similar than different. One big difference, however, is that Zowie hasn’t updated the EC1 as frequently. While the company has announced an EC1-C with a braided cable and lower weight, it’s yet to really make its way to market. So, we’re still recommending the older EC1 for the time being.

The EC1 is a blast from the past, in both good and bad ways. On the positive side, it’s a refreshingly no-frills gaming mouse: there’s no RGB, onboard profiles, or any drivers. It’s a purely plug-and-play mouse with four DPI (400, 800, 1600, and 3200) and three polling rate (100, 250, 1000 Hz) settings, all accessible from the mouse itself.

While the four DPI settings should be enough for most gamers, they will be a bit limited if you prefer in-between values. The EC1 probably isn’t the gaming mouse for you if you’re a stickler for ultra-precise DPI settings. If that’s the case, you’ll want a newer gaming mouse with more extensive software customization.

That brings us to the downsides of the EC1. Firstly, it’s a bit on the heavy side for a modern gaming mouse. While 94 grams (3.31 oz) isn’t too bad, it’s still less than ideal. Secondly, the relatively stiff rubber cable pales compared to the lightweight braided offerings that are all the rage now. It’s nothing you can’t solve with a good mouse bungee, but it’s definitely outdated.

Despite that, though, there’s a lot to like about the Zowie EC1. It’s simple, has a tried-and-tested shape, and is priced competitively. It’s beginning to show its age, but it’s still an excellent gaming mouse even in 2021. And if the weight and cable are issues for you, keep an eye out for the EC1-C, which should hopefully be more readily available soon.

3. Microsoft Pro Intellimouse

Sure, the first two mice both have a lot of history behind them. But if you’re after a genuinely classic large gaming mouse, nothing compares to the Microsoft Pro Intellimouse. The body’s barely changed since 1999’s Intellimouse Explorer, which itself was good enough to inspire the Zowie EC1 directly.

The biggest difference between the Microsoft and Zowie shapes is how the former widens to about 2.7 inches towards the rear. It’s a much wider rear than the Zowie, but the other curves are very similar.

The Pro Intellimouse features a modern PixArt PAW3389 sensor for class-leading tracking and performance. Other contemporary features include a braided cable, subtle RGB lighting, and programmable buttons (thumb buttons and mouse wheel click). Not the most exciting features, but the Pro Intellimouse is all about refreshing a safe, respected shape. On that front, it’s mostly a success.

It’s not perfect, of course. The braided cable, while decent, doesn’t have anything close to the flexibility of a modern paracord-style offering from Razer or Glorious. The 140-gram (4.94-oz) weight also makes it quite cumbersome to use, even compared to the Razer DeathAdder V2 Pro or Zowie EC1.

Customization is limited, and Microsoft’s Mouse and Keyboard Center feels quite outdated compared to the competition. But these are arguably small prices to pay if the shape works for you.

The weight is the only thing that keeps the Pro Intellimouse below the DeathAdder V2 Pro and Zowie EC1 in our ranking. But the solid build quality, no-frills design, and sub-$60 price are all strong points in its favor. If weight isn’t an issue, we think you’ll be just as happy with this as the other two.

4. SteelSeries Rival 310

SteelSeries has released many wide gaming mice over the years, and the Rival 310 is a solid addition to that list. The Rival 310 combines a high-quality sensor and Intellimouse-derived ergonomic design with a price that’s often around or below $40, making it an excellent value pick.

The Rival 710’s main claim to fame is the in-house TrueMove3 optical sensor. SteelSeries claims that it offers low latency “true 1 to 1 tracking” with zero hardware mouse acceleration. The sensor is often the most praised aspect of the Rival mice, so it’s probably not just marketing speak here. Either way, it’s at least on par with other top-quality sensors, so you’re not sacrificing performance in the name of a lower price.

Other notable hardware specs include switches designed in collaboration with Omron, with a rated lifespan of “50 million clicks”. Admittedly, 50 million isn’t as unique as it used to be, especially when Razer’s optical switches quote a 70-million click lifespan. But it’s another solid example of how the Rival 310 offers a lot of quality hardware for its current pricing.

There’s also onboard memory, which lets you use it without the software (SteelSeries Engine) once you’ve set it up to your liking. Happen to own other SteelSeries RGB gear? The Rival 310 is PrismaSync-equipped, letting you synchronize your RGB lighting across it and other SteelSeries peripherals.

Overall, the SteelSeries Rival 310 offers quite a lot for the price. But that’s because the mouse is a bit old, having come out in 2017. That isn’t a bad thing, but it does mean that the cable is a mid-2010s rubbery affair instead of the flexible paracord-style cables standard in 2021. You also don’t get the slick PTFE feet of the Razer DeathAdder V2 Pro.

So it’s not perfect and is beginning to show its age. But there’s still a lot to like about the Rival 310, especially if you want a gaming mouse that’s extra-wide at the rear. The fact that it’s less than $50 makes it all the better.

5. Logitech G604

Want a large gaming mouse that uses the extra real estate to add more buttons? Well, then the Logitech G604 is for you. Unlike the other gaming mice on this list, the G604 goes for the maximalist approach, boasting 15 programmable buttons on its large body.

You get six thumb buttons, DPI up and down, and mouse wheel left and right clicks alongside the standard five mouse buttons. If 15 programmable functions aren’t enough, you can map a G Shift button that gives you access to an extra layer of bindings when held down (much like the Function key on a keyboard).

You also get a non-programmable wheel mode toggle button below the scroll wheel. This lets you choose between the G604’s two mouse wheel modes. One offers you a freewheeling scroll that’s great for scrolling through long menus or websites, while the other is a slower scroll with clearly defined notches if you want precision.

If you’re an MMO or MOBA gamer, then this is the perfect gaming mouse for you. Productivity-minded users may also enjoy the G604, as Logitech’s G Hub software lets you map buttons to your preferred key combinations or macros.

It’s not all about the extra buttons, though. The G604 boasts Logitech’s latest HERO 25K sensor (boasting a frankly insane 25,600 DPI maximum) and the company’s Lightspeed wireless technology for a low-latency wireless gaming experience. So the G604 will still do the job even in games where you don’t need those extra thumb buttons.

However, the 135 gram (4.76 oz) weight will likely be an issue for more competitive FPS gamers. The AA battery powering the G604 is to blame for the extra weight, but it does mean an impressive 240-hour battery life. So there’s at least an upside to the G604’s heft.

Overall, the Logitech G604 is a versatile computer mouse that will appeal to both gamers and professionals. It covers a lot of bases, whether you need the extra buttons for MMO binds or just want 240 hours of wireless use for working on the go.

Closing Thoughts

Just because big gaming mice aren’t as common as their smaller counterparts doesn’t mean you have to settle for lower-quality mice. Sure, you’ll mostly be looking at older or refreshed models, but there are still a lot of good mice out there for those of you that find the modern ultralights too small.

Overall, we think the Razer DeathAdder V2 Pro is the best gaming mouse for large hands. But it’s a case of fine margins here, and we think you’ll be happy with any of the first four mice here. The Logitech G604 is a bit of an outlier, but it’s probably the gaming mouse you want if you need more than the standard five or six buttons.